Search results for " Barrett"

Early miR-223 Upregulation in Gastroesophageal Carcinogenesis

2017

Objectives: To test miR-223 upregulation during gastric (intestinal-type) and Barrett esophageal carcinogenesis. Methods: miR-223 expression was assessed by quantitative reverse transcription polymerase chain reaction in a series of 280 gastroesophageal biopsy samples representative of the whole spectrum of phenotypic changes involved in both carcinogenetic cascades. The results were further validated by in situ hybridization on multiple tissue specimens obtained from six surgically treated gastroesophageal adenocarcinomas. miR-223 expression was also assessed in plasma samples from 30 patients with early stage (ie, stages I and II) gastroesophageal adenocarcinoma and relative controls. Res…

The phenotype of gastric mucosa coexisting with Barrett's oesophagus.

2001

Barrett's oesophagus complicates the gastro-oesophageal acid reflux. Helicobacter pylori infection, particularly with cagA positive strains, induces inflammatory/atrophic lesions of the gastric mucosa, which may impair acid output. No systematic study has investigated the phenotype of the gastric mucosa coexisting with Barrett's oesophagus. This study was designed to identify the phenotype of gastric mucosa associated with Barrett's oesophagus.In this retrospective case control study, the phenotype of the gastric mucosa was histologically characterised in 53 consecutive patients with Barrett's oesophagus and in 53 (sex and age matched) non-ulcer dyspeptic controls. Both patients and control…

Aurora-A overexpression as an early marker of reflux-related columnar mucosa and Barrett's oesophagus.

2007

Abstract BACKGROUND: The development of oesophageal adenocarcinoma is generally closely associated with the presence of a specialised intestinal-type epithelium such as that found in Barrett's oesophagus (BO). A particular histological condition is when the distal oesophagus showing cardiac and/or fundic mucosa without intestinal metaplasia cannot be defined as 'Barrett's mucosa' [condition that we call 'columnar-lined oesophagus' (CLO)] and up till now, there has been no agreement in literature about the management of this condition. Aurora-A overexpression leads to centrosome amplification, chromosomal instability and aneuploidy in mammalian cells. PATIENTS AND METHODS: A prospective stud…

CD1a expression in Barrett’s oesophagus: new role for an old molecule against metaplastic progression

2005

Columnar-Lined Esophagus CK7 Positive is an Early Marker of Gastroesophageal Reflux Disease

2011

LETTER TO EDITOR

CD1a expression in primary breast cancer and lymph nodes: correlation with clinicopathological parameters.

2006

L'Esofago di Barrett

2009

Prefazione alla monografia "L'Esofago di Barrett. Valutazioni personali dell'endoscopista e analisi delle più recenti acquisizioni"

Helicobacter pylori and Barrett’s esophagus: a protective factor or a real cause?

2017

Nothwithstanding the definite aethiopathogenetic path of certain diseases, the relationship between Helicobacter Pylori (H. Pylori) and barrett's esophagus (BE), a condition that increases the risk for dysplasia and consequently adenocarcinoma of the distal esophagus and esophagogastric junction, remains uncertain. this paper reviews the current scientific literature with emphasis on the protective correlation between H. Pylori infection and BE, and demonstrates that a causal relathionship has not been disproved with certainty. Furthermore, H. Pylori infection could pose a risk for the onset of gastroesophageal reflux disease (GERD), which could in turn trigger BE, a precancerous lesion and…

L'ESOFAGO DI BARRETT - Valutazioni personali dell'endoscopista ed analisi delle più recenti acquisizioni scientifiche

2009

L’intento di questa monografia è quello di stimolare un momento di riflessione e di confronto, sull'"Esofago di Barrett". L’autore ha messo a confronto, quanto acquisito in quasi 20 anni di attività endoscopica, con le acquisizioni più recenti riportate in letteratura. Questa patologia, è considerata essere una condizione pre-cancerosa in quanto può evolvere, ma fortunatamente, non in tutti, verso il tumore dell’esofago. L’esofago di Barrett, ritengo corretto considerarlo una “patologia di interesse emergente”. L’affinamento delle metodiche diagnostiche, unitamente ai programmi di screening stimolati dalla maggiore consapevolezza, ha fatto si, che questa condizione patologica, sia sempre pi…

Laparoscopic Nissen fundoplication and short segment Barrett's esophagus

2010